Gene name:
Hnrnpu (Hnrpu) ;
Protein name:
Heterogeneous nuclear ribonucleoprotein U (hnRNP U) ;
Alternative:
Scaffold attachment factor A (SAF-A) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Identified in the spliceosome C complex. Component of the coding region determinant (CRD)-mediated complex, composed of DHX9, HNRNPU, IGF2BP1, SYNCRIP and YBX1. Identified in a mRNP complex, at least composed of DHX9, DDX3X, ELAVL1, HNRNPU, IGF2BP1, ILF3, PABPC1, PCBP2, PTBP2, STAU1, STAU2, SYNCRIP and YBX1. Identified in a mRNP granule complex, at least composed of ACTB, ACTN4, DHX9, ERG, HNRNPA1, HNRNPA2B1, HNRNPAB, HNRNPD, HNRNPL, HNRNPR, HNRNPU, HSPA1, HSPA8, IGF2BP1, ILF2, ILF3, NCBP1, NCL, PABPC1, PABPC4, PABPN1, RPLP0, RPS3, RPS3A, RPS4X, RPS8, RPS9, SYNCRIP, TROVE2, YBX1 and untranslated mRNAs. Interacts with IGF2BP1 and ERBB4. Ligand for CR2.
Function:
Component of the CRD-mediated complex that promotes MYC mRNA stabilization. Binds to pre-mRNA. Has high affinity for scaffold-attached region (SAR) DNA. Binds to double- and single-stranded DNA and RNA.
Subcellular Location:
Nucleus
Cytoplasm
Cell surface
Localized in cytoplasmic mRNP granules containing untranslated mRNAs. Component of ribonucleosomes. Also found associated with the cell surface.
Protein Attributes:
50:
MSSSPVNVKK | LKVSELKEEL | KKRRLSDKGL | KADLMDRLQA | ALDNEAGGRP |
100:
AMEPGNGSLD | LGGDAAGRSG | AGLEQEAAAG | AEDDEEEEGI | AALDGDQMEL |
150:
GEENGAAGAA | DAGAMEEEEA | ASEDENGDDQ | GFQEGEDELG | DEEEGAGDEN |
200:
GHGEQQSQPP | AAAAQQQPSQ | QRGAGKEAAG | KSSGPTSLFA | VTVAPPGARQ |
250:
GQQQAGGDGK | TEQKGGDKKR | GVKRPREDHG | RGYFEYIEEN | KYSRAKSPQP |
300:
PVEEEDEHFD | DTVVCLDTYN | CDLHFKISRD | RLSASSLTME | SFAFLWAGGR |
350:
ASYGVSKGKV | CFEMKVTEKI | PVRHLYTKDI | DIHEVRIGWS | LTTSGMLLGE |
400:
EEFSYGYSLK | GIKTCNCETE | DYGEKFDEND | VITCFANFET | DEVELSYAKN |
450:
GQDLGVAFKI | SKEVLADRPL | FPHVLCHNCA | VEFNFGQKEK | PYFPIPEDCT |
500:
FIQNVPLEDR | VRGPKGPEEK | KDCEVVMMIG | LPGAGKTTWV | TKHAAENPGK |
550:
YNILGTNTIM | DKMMVAGFKK | QMADTGKLNT | LLQRAPQCLG | KFIEIAARKK |
600:
RNFILDQTNV | SAAAQRRKMC | LFAGFQRKAV | VVCPKDEDYK | QRTQKKAEVE |
650:
GKDLPEHAVL | KMKGNFTLPE | VAECFDEITY | VELQKEEAQK | LLEQYKEESK |
700:
KALPPEKKQN | TGSKKSNKNK | SGKNQFNRGG | GHRGRGGFNM | RGGNFRGGAP |
750:
GNRGGYNRRG | NMPQRGGGGG | SGGIGYPYPR | GPVFPGRGGY | SNRGNYNRGG |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Mouse hnRNP U
ELISA Kit for Mouse hnRNP U
CLIA Kit for Mouse hnRNP U
CLIA Kit for Mouse hnRNP U
Polyclonal Antibody for Mouse hnRNP U
Polyclonal Antibody for Mouse hnRNP U
Monoclonal Antibody for Mouse hnRNP U
Monoclonal Antibody for Mouse hnRNP U
Protein for Mouse hnRNP U
Protein for Mouse hnRNP U
R&D Technical Data
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Lung .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Mammary tumor .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Brain .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-242;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Mast cell .
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-58 AND SER-247;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Liver .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-58 AND SER-247;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-17; LYS-21; LYS-181; LYS-241 AND LYS-328;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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Embryonic fibroblast .